Intro

I work with stem cells in the lab, so I want to share the information on that topic at that blog. There are lots of interesting articles and study materials about stem cells on the web that's why I'm trying to gather them all here.

8/29/2014

Gremlins Sabotage the Mechanisms of Cancer Stem Cell Differentiation

Gremlins Sabotage the Mechanisms of Cancer Stem Cell Differentiation - that's not a joke. It's a title of the new paper at Cancer Cell Volume 25, Issue 6, 16 June 2014, Pages 716–717. Joan Seoane made an interesting research on cancer stem cells. 
Here is the abstract: BMP is highly expressed in glioblastoma and promotes differentiation of cancer stem cells (CSCs). Recently, Yan and colleagues found the explanation to this apparent paradox by showing that the antagonist of BMP, Gremlin1, is secreted by CSCs to protect them against the BMP-induced differentiation.

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