The reconstruction of rat penis with stem cells!

Wow. Scientists are able to reconstruct almost every organ in our body. The latest news:

Men in need of penis reconstruction could soon enjoy the benefits of a special ingredient: stem cells. A new study in rats shows that lacing a penis graft with adult stem cells yields better healing and sexual function than using the graft alone. The finding may point the way to improved treatments for a variety of human penile impairments.
Men with penis injuries, deformities, or severe Peyronie's disease—which causes excessive scarring that can curve or shrink the penis—sometimes need surgery to reconstruct their genitalia and restore their sexual function. Many receive a graft made of their own tissue, cadaver tissue, or pig intestines, but the surgery can cause complications, including erectile dysfunction.

Sperm from the Artificial Testicle!

Stem cell researchers are going to develop in vitro an important part of male's organism - testicle with sperm! More about the event was written by: Rachael Rettner, MyHealthNewsDaily Staff Writer
Published: 01/18/2012 05:20 PM EST on MyHealthNewsDaily

Researchers in California hope to become the first in the world to build an artificial testicle that produces human sperm. Such a device could allow infertile men to conceive children.

While recent studies have shown it's possible to treat infertile male mice by producing sperm using stem cells from the mouse, the same has not been done for humans, said researcher Dr. Paul Turek, director of the Turek Clinic, a men's health medical practice in San Francisco.

Using a newly received government grant, Turek and his fellow researchers hope to develop a human "sperm-making biological machine," he said.

Unlike a non-sperm-producing prosthesis — a saline-filled implant for men missing a testicle — the device will not be designed to resemble a testicle. Instead it will most closely resemble a cylindrical bag a few inches long, Turek said, creating a final product that looks something like a transparent, over-sized Tootsie Roll.

Stem Cell Research Problems

Another one opinion on stem cell research:

A lot has been written and also said about stem cell research, and most of these trumpet about ultimately locating a cure for several ailments. Nevertheless, presently there are also camps that absolutely dismiss the stem cell research pros, while focusing on its purportedly damaging aspects. But before many of us live on the stem cell research disadvantages, allow us very first discuss exactly what come cellular material are regarding. Originate cells produce fresh blood vessels tissues, which is why they will are considered as the blood’s human being building blocks. The thing that makes come cells particular is the simple fact that they can possibly become various kinds of cells, which usually in switch may be developed into specialized cellular material that may be used by scientists in their own search for ways to repair bodily organs that have by now sustained harm.
Of the a couple of vast forms of stem tissues observed in mammals, embryonic base cells are the versions that could possibly grow into other kinds of tissues. Very easily stored in a laboratory, embryonic base cellular material, are additionally special in the feeling that they are able to identical them selves in countless amounts, along with forever with that.
This quality on your own means they are ideal for scientific utilize along with ongoing stem cell research. Most of this reports have already proven that serious diseases similar to ms, Parkinson's along with Alzheimer's is treatable with the assistance of come tissue. That perhaps retains the potential to the treatment of heart disease, strokes, kidney disease, liver disease, pancreas disease and also arthritis, as well as discovering a treat for cancer malignancy.
But for almost all the stem cell research pros, some groupings notice the concerns in the idea. Much of the stem cell research downsides that that they are professing are moral in character. These people say that because embryonic come cells are in truth little embryos, just what stem mobile researchers are tinkering with is living. Almost all of those who take this distinct argument are those which consider that existence starts with conception, certainly not at start, as just what is typically accepted.
The problem of cloning has also hounded stem cellular scientists, which profess they only rely on them for research functions, not necessarily to clone another individual. Nevertheless whichever the problems for or versus stem cell research are, the truth remains that teens is on the verge involving a main health-related as well as scientific jump, one that can modify the globe once and for all.

http://shyfish.info/a-peek-at-each-side-in-the-stem-cell-studies-discussion/ 

Stem Cells & Future Medicine (important opinion)

I'd like to share an interesting opinion from Sara Rankin, Professor of Leukocyte and Stem Cell Biology at Imperial College London's Faculty of Medicine, turns the spotlight onto the future impact of stem cell therapy:

Canadian scientists investigating the effects of radiation on the human body 50 years ago discovered that bone marrow 1contains stem cells that provide a lifelong supply of blood cells. This discovery paved the way for the first stem cell therapy – in the form of bone marrow transplants – using bone marrow stem cells from healthy donors to treat patients with genetic blood disorders and leukaemias.

Scientists went on to show that in addition to the bone marrow, almost every tissue in the body, including heart, brain, teeth and gut, contain tissue-specific stem cells. The function of these stem cells is to repair or regenerate tissues that are constantly being damaged as a result of general wear and tear – for example, replacing the lining of the gut as it is being sloughed off or generating new blood cells as they die or are destroyed. Such tissue-specific stem cells are also known as adult stem cells, simply because they are found in adult tissues. These adult stem cells are distinct from embryonic (ES) stem cells that are only found in embryos.

MSCs in Clinical Research (best reviews, part-2)

Trounson, A., Thakar, R., Lomax, G., & Gibbons, D. (2011). Clinical trials for stem cell therapies BMC Medicine, 9 (1) DOI: 10.1186/1741-7015-9-52

      Bernardo, M., Pagliara, D., & Locatelli, F. (2011). Mesenchymal stromal cell therapy: a revolution in Regenerative Medicine? Bone Marrow Transplantation DOI: 10.1038/bmt.2011.81

Siniscalco, D., Giordano, A., & Galderisi, U. (2011). Novel insights in basic and applied stem cell therapy Journal of Cellular Physiology DOI: 10.1002/jcp.22945

From Stem Cell TV

Interesting video!

Education (stem cell topic)

Beautiful stem cell education resource: http://www.tellmeaboutstemcells.org/

The Best Mesenchymal Stem Cell Reviews (part 1)

I'm involved in MSC-research and I love brilliant articles on that topic. The list of my favorite reviews about Mesenchymal Stem Cells is here now:


Klopp, A., Gupta, A., Spaeth, E., Andreeff, M., & Marini, F. (2011). Concise Review: Dissecting a Discrepancy in the Literature: Do Mesenchymal Stem Cells Support or Suppress Tumor Growth? STEM CELLS, 29 (1), 11-19 DOI: 10.1002/stem.559
KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY
Volume 17, Number 11, 1289-1297, DOI: 10.1007/s00167-009-0782-4

A Comprehensive Review on Mesenchymal Stem Cell Growth and Senescence Krzysztof Książek. Rejuvenation Research. April 2009, 12(2): 105-116. doi:10.1089/rej.2009.0830.




Kim, S., & de Vellis, J. (2009). Stem cell-based cell therapy in neurological diseases: A review Journal of Neuroscience Research, 87 (10), 2183-2200 DOI: 10.1002/jnr.22054




Stem Cells Trans MedDecember 2011sctm.2011-0024
Concise Review: Clinical Translation of Wound Healing Therapies Based on Mesenchymal Stem Cells
Wesley M. Jackson, Leon J. Nesti, and Rocky S. Tuan

Inflammation and mesenchymal stem cell aging Gunter Lepperdinger
Current Opinion in Immunology Volume 23, Issue 4, August 2011, Pages 518-524
doi:10.1016/j.coi.2011.05.007

And the very best:

Karp, J., & Leng Teo, G. (2009). Mesenchymal Stem Cell Homing: The Devil Is in the Details Cell Stem Cell, 4 (3), 206-216 DOI: 10.1016/j.stem.2009.02.001





To be continued...

Stemmy!111 ^_^

So cuuuuute!11111

And more about Stemmy:

Aaaaaannnnnddddd moooooooreeee:

Pictures from http://www.terry.ubc.ca/2009/08/07/faq-stem-cells-sa-mix/, moreover you can find text there.